Genesis Reviews
- Shining in the Darkness
- Shinobi III: Return of the Ninja Master
- Shove It! The Warehouse Game
- Shui Hu Feng Yun Zhuan
- Simpsons: Bart vs. the Space Mutants
- Simpsons: Bart's Nightmare
- Simpsons: Krusty's Super Fun House
- Simpsons: Virtual Bart
- Skeleton Krew
- Skitchin'
- Slap Fight
- Slaughter Sport
- Smurfs
- Smurfs 2: Smurfs Travel the World
- Snake, Rattle 'n Roll
- Snow Bros. Starring Nick & Tom
- Socket
- Sol-Deace
- Soldiers of Fortune
- Sonic & Knuckles
- Sonic 3D Blast
- Sonic Classics
- Sonic Spinball
- Sonic The Hedgehog
- Sonic The Hedgehog 2
- Sonic The Hedgehog 3
- Sorcerer's Kingdom
- Sorcerian
- Space Harrier II
- Space Invaders '91
- Space Turtle Ship (Uzu Keobukseon)
- Sparkster
- Speedball 2: Brutal Deluxe
- Spider-Man & Venom: Maximum Carnage
- Spider-Man & Venom: Separation Anxiety
- Spider-Man vs. the Kingpin
- Spider-Man X-Men: Arcade's Revenge
- Spider-Man: The Animated Series
- Spiritual Warfare
- Splatterhouse 2
- Splatterhouse 3
- Sports Talk Baseball
- Spot Goes to Hollywood
- Star Control
- Star Odyssey
- Star Trek: Deep Space Nine: Crossroads of Time
- Starflight
- Stargate
- Steel Empire
- STNG: Echoes from the Past
